Grand Duke Henri became Hereditary Grand Duke of Luxembourg on 12 November 1964 and was educated in Luxembourg and in France, where he obtained his baccalaureate in 1974. He then studied political sciences at University of Geneva, graduating in 1980. The Grand Duke also undertook military officer training at the Royal Military Academy Sandhurst, England.
- Prince Guillaume Jean Joseph Marie, Hereditary Grand Duke of Luxembourg (11 November 1981)
- Prince Félix Léopold Marie Guillaume (3 June 1984)
- Prince Louis Xavier Marie Guillaume (3 August 1986)
- Prince Gabriel Michael Louis Ronny of Nassau (born 12 March 2006)
- Prince Noah Guillaume of Nassau (born 21 September 2007)
- Princess Alexandra Joséphine Teresa Charlotte Marie Wilhelmine (16 February 1991)
- Prince Sébastien Henri Marie Guillaume (16 April 1992)